The botanical name is 'Hypericum Perforatum', this plant has a yellow flower with a long history originally named for the feast of John the Baptist. The old english word for plant is 'wort'.This is the most popular herbal supplement for treatment of depression.
It contains a vast array of chemical compounds. of which Hyperforin is the most beneficial. Studies show that the measured amounts of the active ingredients varies considerably depending on the commercial preparation.
Action
Hyerian and hyperforin have been found to inhibit the reuptake of serotonin, dopamine and norepinephrine into the neural path . These pay a beneficial role in treatment of mild to moderately severe depression.
Caution
Before taking St Johns Wort, patients should discuss this with their doctor and/or pharmacist since there may be a problematic interactive effect when taken in conjuction with other substances.
Medscape Review 24/12/09
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